| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PRG2 |
| Specificity: |
This antibody reacts specifically with PRG2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PRG2 |
| Gene ID: |
5553 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternatively spliced transcript variants encoding different isoforms have been found for this gene, Aug 2011], High levels of the proform of this protein are also present in placenta and pregnancy serum, It is directly implicated in epithelial cell damage, This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, [provided by RefSeq, and C3dg, and bronchospasm in allergic diseases, and in immune hypersensitivity reactions, angiotensinogen (AGT), exfoliation, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MBP BMPG proMBP |
| Also known as: |
PRG2 Polyclonal Antibody |
| Other name: |
Anti-PRG2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PRG2 |
| Short name: |
Anti-PRG2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, bone marrow (natural killer cell activator, eosinophil granule major basic protein) (polyclonal), antibody to-proteoglycan 2 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BMPG and MBP and MBP1, Extracellular, PRG2 and IDBG-46552 and ENSG00000186652 and 5553, Prg2 and IDBG-185619 and ENSMUSG00000027073 and 19074, bone marrow (natural killer cell activator, carbohydrate binding, eosinophil granule major basic protein), this GO :0002215 and defense response to nematode and biological process this GO :0005576 and extracellular region and cellular component this GO :0006955 and immune response and biological process this GO :0008201 and heparin binding and molecular function this GO :0030133 and transport vesicle and cellular component this GO :0030246 and carbohydrate binding and molecular function this GO :0032693 and negative regulation of interleukin-10 production and biological process this GO :0032753 and positive regulation of interleukin-4 production and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0008201 : heparin binding, this GO :0008201 : heparin binding and also this GO :0030246 : carbohydrate binding, this GO :0030246 : carbohydrate binding, proteoglycan 2 |
| Identity: |
9362 |
| Gene: |
PRG2 |
More about : PRG2 |
| Long gene name: |
pro eosinophil major basic protein , proteoglycan 2 |
| Synonyms gene name: |
bone marrow (natural killer cell activator, eosinophil granule major basic protein) , proteoglycan 2 |
| Synonyms name: |
eosinophil major basic protein |
| Locus: |
11q12, 1 |
| Discovery year: |
1993-09-29 |
| GenBank acession: |
BC005929 |
| Entrez gene record: |
5553 |
| Pubmed identfication: |
1565101 |
| RefSeq identity: |
NM_002728 |
| Classification: |
C-type lectin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000167027 |