| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SPOP |
| Specificity: |
This antibody reacts specifically with SPOP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SPOP |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternative splicing of this gene results in multiple transcript variants encoding the same protein, In mouse, Jul 2008], The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes, [provided by RefSeq, a variant H2A histone that is enriched on inactivated X chromosomes, and other histone-associated proteins, core histones, the encoded protein binds to the putative leucine zipper domain of macroH2A1, which interacts with histone deacetylase, 2, This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
TEF2 BTBD32 |
| Also known as: |
SPOP Polyclonal Antibody |
| Other name: |
Anti-SPOP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SPOP |
| Short name: |
Anti-SPOP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-SPOP (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11254 |
| Gene: |
SPOP |
More about : SPOP |
| Long gene name: |
speckle type BTB/POZ protein |
| Synonyms gene name: |
speckle-type POZ protein |
| Locus: |
17q21, 33 |
| Discovery year: |
1998-09-07 |
| GenBank acession: |
AJ000644 |
| Entrez gene record: |
8405 |
| Pubmed identfication: |
9414087 |
| RefSeq identity: |
NM_003563 |
| Classification: |
BTB domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000161496 |