| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Rad23 |
| Specificity: |
This antibody reacts specifically with Rad23 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from Saccharomyces cerevisiae Rad23 |
| Gene ID: |
856674 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Yeast |
| Cross Reactive Species details: |
Saccharomyces cerevisiae |
| Background information: |
In addition to a role in DNA repair events in yeast, Its carboxy-terminal ubiquitin-associated domain is evolutionarily conserved from yeast to humans (4), RAD18, RAD2, RAD23 bears a ubiquitin-like domain at its amino terminus and this ubiquitin-like domain affects protein function in a nonproteolytic manner (3), RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function (3), RAD23 resembles the other DNA repair genes, RAD6, RAD7, Rad23 is a highly conserved protein involved in nucleotide excision repair (NER) that associates with the proteasome via its amino-terminus (4), all of which also exhibit increased transcription in response to DNA damage and during meiosis (2), and RAD54, several lines of evidence indicate that the Rad23 protein may regulate the activity of the 26 S proteasome (5), The RAD23 gene of Saccharomyces cerevisiae is required for excision-repair of UV damaged DNA (1) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HHR23A MGC111083 |
| Also known as: |
Rad23 Polyclonal Antibody |
| Other name: |
Anti-Rad23 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Rad23 |
| Short name: |
Anti-Rad23 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Rad23 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9812 |
| Gene: |
RAD23A |
More about : RAD23A |
| Long gene name: |
RAD23 homolog A, nucleotide excision repair protein |
| Synonyms gene name: |
RAD23 (S, cerevisiae) , cerevisiae) homolog A RAD23 homolog A (S |
| Synonyms name: |
A , RAD23, yeast homolog |
| Locus: |
19p13, 13 |
| Discovery year: |
1994-07-20 |
| Entrez gene record: |
5886 |
| Pubmed identfication: |
7851894 21676658 |
| RefSeq identity: |
NM_005053 |
| Classification: |
Nucleotide excision repair |
| Havana BLAST/BLAT: |
OTTHUMG00000180723 |