| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CLIC4 |
| Specificity: |
This antibody reacts specifically with CLIC4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CLIC4 |
| Gene ID: |
25932 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Channel activity depends on the pH, Could also promote endothelial cell proliferation and regulate endothelial morphogenesis, Expression is prominent in heart, Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis, Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, Promotes cell-surface expression of HRH3, esophagus and kidney (at protein level), kidney, placenta and skeletal muscle, Can insert into membranes and form poorly selective ion channels that may also transport chloride ions, Tissue specificity: Detected in epithelial cells from colon |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DKFZP566G223 CLIC4L P64H1 H1 huH1 p64H1 |
| Also known as: |
CLIC4 Polyclonal Antibody |
| Other name: |
Anti-CLIC4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CLIC4 |
| Short name: |
Anti-CLIC4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CLIC4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13518 |
| Gene: |
CLIC4 |
More about : CLIC4 |
| Long gene name: |
chloride intracellular channel 4 |
| Locus: |
1p36, 11 |
| Discovery year: |
2000-10-31 |
| GenBank acession: |
AF097330 |
| Entrez gene record: |
25932 |
| Pubmed identfication: |
9139710 10070163 |
| RefSeq identity: |
NM_013943 |
| Classification: |
Chloride intracellular channels |
| Havana BLAST/BLAT: |
OTTHUMG00000003327 |