| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Neutrophil Elastase |
| Specificity: |
This antibody reacts specifically with Neutrophil Elastase |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Neutrophil Elastase |
| Gene ID: |
1991 |
| Swiss Prot: |
P08246 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Inhibits C5a-dependent neutrophil enzyme release and chemotaxis, monocytes and granulocytes, Modifies the functions of natural killer cells |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NE HNE HLE |
| Also known as: |
Neutrophil Elastase Polyclonal Antibody |
| Other name: |
Anti-Neutrophil Elastase Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Neutrophil Elastase |
| Short name: |
Anti-Neutrophil Elastase (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Neutrophil Elastase (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3309 |
| Gene: |
ELANE |
More about : ELANE |
| Long gene name: |
elastase, neutrophil expressed |
| Synonyms gene: |
ELA2 |
| Synonyms gene name: |
elastase 2, neutrophil |
| Synonyms name: |
neutrophil elastase leukocyte elastase medullasin |
| Locus: |
19p13, 3 |
| Discovery year: |
1989-09-08 |
| Entrez gene record: |
1991 |
| Pubmed identfication: |
2902087 |
| RefSeq identity: |
NM_001972 |
| Havana BLAST/BLAT: |
OTTHUMG00000181839 |
| Locus Specific Databases: |
ELA2base: Mutation registry for Cyclic and congenital neutropenia LRG_57 |