| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LCMV Protein Z |
| Specificity: |
This antibody reacts specifically with LCMV Protein Z |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from LCMV Protein Z |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Virus |
| Cross Reactive Species details: |
Armstrong Strain LCMV |
| Background information: |
Also selectively represses protein production by associating with host eIF4E, Expressed late in the virus life cycle, Plays critical roles in the final steps of viral release by interacting with host TSG101, Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP, The budding of the virus progeny occurs after association of protein Z with the viral glycoprotein complex SSP-GP1-GP2 at the cell periphery, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L (By similarity), step that requires myristoylation of protein Z, Plays a crucial role in virion assembly and budding |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Protein Z, Z_LYCVA, Zinc-binding protein, Lymphocytic choriomeningitis virus, RING finger protein Z |
| Also known as: |
LCMV Protein Z Polyclonal Antibody |
| Other name: |
Anti-LCMV Protein Z Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
LCMV Protein Z |
| Short name: |
Anti-LCMV Protein Z (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-LCMV Protein Z (polyclonal) |
| Alternative technique: |
polyclonals |