| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Calpain 12 |
| Specificity: |
This antibody reacts specifically with Calpain 12 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Calpain 12 |
| Gene ID: |
147968 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Calpain 12 was first described in the mouse, Domains in the large subunit include the amino terminal domain I, Isoforms differ in the carboxyterminal ends, and maps to mouse chromosome 7, and synaptic plasticity, and the EF hand domain IV, cell division, domain III, ending with aberrant domain III and lacking domain IV, making Calpain 12 most similar to calpains 1 and 2, modulation of integrin and cytoskeletal interactions, most strongly in the skin, the proteinase domain II, Calpains are a family of cytosolic calcium activated cysteine proteases involved in a variety of cellular processes including apoptosis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Calpain 12 Polyclonal Antibody |
| Other name: |
Anti-Calpain 12 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Calpain 12 |
| Short name: |
Anti-Calpain 12 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Calpain 12 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
13249 |
| Gene: |
CAPN12 |
More about : CAPN12 |
| Long gene name: |
calpain 12 |
| Locus: |
19q13, 2 |
| Discovery year: |
2004-10-20 |
| GenBank acession: |
BC014027 |
| Entrez gene record: |
147968 |
| Classification: |
Calpains EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000182525 |