| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Dystrophin |
| Specificity: |
This antibody reacts specifically with Dystrophin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Dystrophin/DMD |
| Gene ID: |
1756 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also implicated in signaling events and synaptic transmission, Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma, Expressed in brain, Isoform 5 is expressed in heart, Ligand for dystroglycan, Most tissues contain transcripts of multiple isoforms, brain, however only isoform 5 is detected in heart and liver, kidney, liver, lung and testis, muscle, testis and hepatoma cells, Anchors the extracellular matrix to the cytoskeleton via F-actin, Tissue specificityExpressed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
Dystrophin Polyclonal Antibody |
| Other name: |
Anti-Dystrophin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Dystrophin |
| Short name: |
Anti-Dystrophin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Dystrophin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3032 |
| Gene: |
DRP2 |
More about : DRP2 |
| Long gene name: |
dystrophin related protein 2 |
| Locus: |
Xq22, 1 |
| Discovery year: |
1996-07-17 |
| GenBank acession: |
U43519 |
| Entrez gene record: |
1821 |
| Pubmed identfication: |
8640231 |
| RefSeq identity: |
NM_001939 |
| Classification: |
Zinc fingers ZZ-type |
| Havana BLAST/BLAT: |
OTTHUMG00000022020 |
| Locus Specific Databases: |
Mental Retardation database |