| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HRH1 |
| Specificity: |
This antibody reacts specifically with HRH1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human HRH1 |
| Gene ID: |
3269 |
| Swiss Prot: |
P35367 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system, increase in capillary permeability due to contraction of terminal venules, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, In peripheral tissues |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
HRH1 Polyclonal Antibody |
| Other name: |
Anti-HRH1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HRH1 |
| Short name: |
Anti-HRH1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-histamine receptor H1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
H1-R and hisH1, HRH1 and IDBG-18663 and ENSG00000196639 and 3269, HRH1 and IDBG-647815 and ENSBTAG00000001447 and 281231, Hrh1 and IDBG-178946 and ENSMUSG00000053004 and 15465, Plasma membranes, histamine receptor activity, this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004969 and histamine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007200 and phospholipase C-activating G-protein coupled receptor signaling pathway and biological process this GO :0007613 and memory and biological process this GO :0008542 and visual learning and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0032962 and positive regulation of inositol trisphosphate biosynthetic process and biological process this GO :0043114 and regulation of vascular permeability and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0048016 and inositol phosphate-mediated signaling and biological process this GO :0048167 and regulation of synaptic plasticity and biological process this GO :0048245 and eosinophil chemotaxis and biological process this GO :0071420 and cellular response to histamine and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004969 : histamine receptor activity, this GO :0004969 : histamine receptor activity, histamine receptor H1 |
| Identity: |
5182 |
| Gene: |
HRH1 |
More about : HRH1 |
| Long gene name: |
histamine receptor H1 |
| Locus: |
3p25, 3 |
| Discovery year: |
1994-12-12 |
| Entrez gene record: |
3269 |
| Pubmed identfication: |
8003029 |
| Classification: |
Histamine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000129719 |