| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
EZH1 |
| Specificity: |
This antibody reacts specifically with EZH1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human EZH1 |
| Gene ID: |
2145 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Able to mono-, Catalytic subunit of the PRC2/EED-EZH1 complex, Compared to EZH1-containing complexes, EZ subfamily, H3K27me2 and H3K27me3, Required for embryonic stem cell derivation and self-renewal, Sequence similarities Belongs to the histone-lysine methyltransferase family, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, it is less abundant in embryonic stem cells, leading to transcriptional repression of the affected target gene, respectively, suggesting that it is involved in safeguarding embryonic stem cell identity, which is required for embryonic stem cell identity and proper differentiation, which methylates 'Lys-27' of histone H3, Contains 1 SET domain, Polycomb group (PcG) protein |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
KIAA0388 KMT6B |
| Also known as: |
EZH1 Polyclonal Antibody |
| Other name: |
Anti-EZH1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
EZH1 |
| Short name: |
Anti-EZH1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-EZH1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3526 |
| Gene: |
EZH1 |
More about : EZH1 |
| Long gene name: |
enhancer of zeste 1 polycomb repressive complex 2 subunit |
| Synonyms gene name: |
enhancer of zeste (Drosophila) homolog 1 enhancer of zeste homolog 1 (Drosophila) |
| Locus: |
17q21, 2 |
| Discovery year: |
1995-12-21 |
| Entrez gene record: |
2145 |
| Pubmed identfication: |
8921387 |
| RefSeq identity: |
NM_001991 |
| Classification: |
Polycomb repressive complex 2 Lysine methyltransferases Myb/SANT domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000180645 |