| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
SGK3 |
| Specificity: |
This antibody reacts specifically with SGK3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SGK3 |
| Gene ID: |
23678 |
| Swiss Prot: |
Q96BR1 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
K(+) channels: KCNA3/KV1, KCNE1, KCNQ1 and KCNH2/HERG, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, Na(+)/H(+) exchanger: SLC9A3/NHE3, Na(+)/dicarboxylate cotransporter: SLC13A2/NADC1, Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes, Phosphorylates NEDD4L and GSK3B, Plays a role in the regulation of renal tubular phosphate transport and bone density, Positively regulates ER transcription activity through phosphorylation of FLII, SLC1A6/EAAT4 and SLC1A7/EAAT5, Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, and the Na(+)/K(+) ATPase, cell growth, chloride channel: BSND, creatine transporter: SLC6A8, epithelial Ca(2+) channels: TRPV5 and TRPV6, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, glutamate transporters: SLC1A3/EAAT1, membrane transporters, proliferation, survival and migration, 3, Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
SGK3 Polyclonal Antibody |
| Other name: |
Anti-SGK3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
SGK3 |
| Short name: |
Anti-SGK3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 3 (polyclonal), antibody to-serum/glucocorticoid regulated kinase family |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cytoplasm, SGK3 and IDBG-23987 and ENSG00000104205 and 100533105, member 3, this GO :0001558 and regulation of cell growth and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005246 and calcium channel regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005769 and early endosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006950 and response to stress and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005246 : calcium channel regulator activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0015459 : potassium channel regulator activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005246 : calcium channel regulator activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0015459 : potassium channel regulator activity, this GO :0016772 : transferase activity, this GO :0017080 : sodium channel regulator activity, this GO :0017081 : chloride channel regulator activity, this GO :0035091 : phosphatidylinositol binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0017080 : sodium channel regulator activity and also this GO :0017081 : chloride channel regulator activity and also this GO :0035091 : phosphatidylinositol binding, transferring phosphorus-containing groups and molecular function this GO :0017080 and sodium channel regulator activity and molecular function this GO :0017081 and chloride channel regulator activity and molecular function this GO :0030334 and regulation of cell migration and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0042127 and regulation of cell proliferation and biological process this GO :0051090 and regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0055037 and recycling endosome and cellular component this GO :0055085 and transmembrane transport and biological process, 23678, serum/glucocorticoid regulated kinase family |
| Identity: |
10812 |
| Gene: |
SGK3 |
More about : SGK3 |
| Long gene name: |
serum/glucocorticoid regulated kinase family member 3 |
| Synonyms gene: |
SGK2 SGKL |
| Synonyms gene name: |
member 3 , serum/glucocorticoid regulated kinase-like serum/glucocorticoid regulated kinase family |
| Locus: |
8q13, 1 |
| Discovery year: |
1999-08-12 |
| Entrez gene record: |
23678 |
| Pubmed identfication: |
10585774 10548550 |
| Havana BLAST/BLAT: |
OTTHUMG00000164561 |