| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Cathelicidin |
| Specificity: |
This antibody reacts specifically with Cathelicidin |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Calicidin |
| Gene ID: |
820 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Along with the family of proteins known as defensins, CAMP, CAP-18, CRAMP (cathelin-related antimicrobial peptide), CRAMP is expressed in testis, FALL-39 precursor (FALL-39 peptide antibiotic, HSD26) is a cathelicidin anti-microbial protein that contains the antibacterial peptide LL-37 (amino acids 134-170), In contrast to the defensins, It is not found in normal skin epidermis, LL-37 binds to bacterial lipopolysaccharides (LPS) and is a potent chemotactic factor for recruiting mast cells to sites of inflammation, LL-37 is a cysteine-free peptide that can adopt an amphipathic &, LL-37 is present in inflammatory skin diseases that include psoriasis, The mouse and rat ortholog, The secreted protein is expressed primarily in bone marrow, These include precursors of potent antimicrobial peptides that direct antimicrobial activity against various microbial pathogens and also activate mesenchymal cells during wound repair, cathelicidins participate in the first line of defense by preventing local infection and systemic invasion of microbes, cationic anti-microbial protein, dermatitis and nickel contact hypersensitivity, is also part of the cathelicidin family of host defense peptides, spleen, stomach and intestine, sub-acute lupus erthematosus, testis and neutrophils, which are cysteine-rich peptides that fold in â, &circ, «, -helical conformation, -pleated sheets, Cathelicidins are a family of antimicrobial proteins found in the peroxidase-negative granules of neutrophils, aring |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CAP18 FALL39 FALL-39 LL37 |
| Also known as: |
Cathelicidin Polyclonal Antibody |
| Other name: |
Anti-Cathelicidin Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Cathelicidin |
| Short name: |
Anti-Cathelicidin (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Cathelicidin (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
1472 |
| Gene: |
CAMP |
More about : CAMP |
| Long gene name: |
cathelicidin antimicrobial peptide |
| Locus: |
3p21, 31 |
| Discovery year: |
1996-12-12 |
| GenBank acession: |
BC055089 |
| Entrez gene record: |
820 |
| Pubmed identfication: |
7624374 |
| RefSeq identity: |
NM_004345 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000133526 |