| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
WISP1 |
| Specificity: |
This antibody reacts specifically with WISP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human WISP1 |
| Gene ID: |
8840 |
| Swiss Prot: |
O95388 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Adheres to skin and melanoma fibroblasts, Associated with cell survival, Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase, In vitro binding to skin fibroblasts occurs through the proteoglycans, Up-regulates the anti-apoptotic Bcl-X(L) protein, decorin and biglycan, Downstream regulator in the Wnt/Frizzled-signaling pathway |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CCN4 |
| Also known as: |
WISP1 Polyclonal Antibody |
| Other name: |
Anti-WISP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
WISP1 |
| Short name: |
Anti-WISP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 1 inducible signaling pathway protein 1 (polyclonal), antibody to-wingless-classification MMTV integration site family |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Extracellular, WISP1 and IDBG-36325 and ENSG00000104415 and 8840, WISP1 and IDBG-644060 and ENSBTAG00000000707 and 539163, Wisp1 and IDBG-146803 and ENSMUSG00000005124 and 22402, insulin-like growth factor binding, this GO :0001558 and regulation of cell growth and biological process this GO :0005515 and protein binding and molecular function this GO :0005520 and insulin-like growth factor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0016055 and Wnt signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005520 : insulin-like growth factor binding, this GO :0005520 : insulin-like growth factor binding, WNT1 inducible signaling pathway protein 1 |
| Identity: |
12769 |
| Gene: |
WISP1 |
More about : WISP1 |
| Long gene name: |
WNT1 inducible signaling pathway protein 1 |
| Locus: |
8q24, 22 |
| Discovery year: |
1999-01-22 |
| GenBank acession: |
AF100779 |
| Entrez gene record: |
8840 |
| Pubmed identfication: |
9843955 |
| RefSeq identity: |
NM_003882 |
| Classification: |
CYR61/CTGF/NOV matricellular proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000164440 |