| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ENPP2 |
| Specificity: |
This antibody reacts specifically with ENPP2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ENPP2 |
| Gene ID: |
5168 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation, Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, Can hydrolyze, Involved in several motility-related processes such as angiogenesis and neurite outgrowth, Major substrate is lysophosphatidylcholine, May have a role in induction of parturition, Possible involvement in cell proliferation and adipose tissue development, Stimulates migration of melanoma cells, Tumor cell motility-stimulating factor, a modulator of cell motility, and barely ATP, bis-pNPP, in vitro, probably via a pertussis toxin-sensitive G protein, to some extent pNP-TMP, Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
ATX PD-IALPHA |
| Also known as: |
ENPP2 Polyclonal Antibody |
| Other name: |
Anti-ENPP2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ENPP2 |
| Short name: |
Anti-ENPP2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ectonucleotide pyrophosphatase/phosphodiesterase 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
ATX and ATX-X and AUTOTAXIN and LysoPLD and NPP2 and PD-IALPHA and PDNP2, ENPP2 and IDBG-33807 and ENSG00000136960 and 5168, ENPP2 and IDBG-645628 and ENSBTAG00000013165 and 532663, Enpp2 and IDBG-140731 and ENSMUSG00000022425 and 18606, Extracellular, alkylglycerophosphoethanolamine phosphodiesterase activity, this GO :0003676 and nucleic acid binding and molecular function this GO :0003824 and catalytic activity and molecular function this GO :0004528 and phosphodiesterase I activity and molecular function this GO :0004551 and nucleotide diphosphatase activity and molecular function this GO :0004622 and lysophospholipase activity and molecular function this GO :0005044 and scavenger receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006796 and phosphate-containing compound metabolic process and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0006928 and cellular component movement and biological process this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008152 and metabolic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009395 and phospholipid catabolic process and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0030247 and polysaccharide binding and molecular function this GO :0030334 and regulation of cell migration and biological process this GO :0034638 and phosphatidylcholine catabolic process and biological process this GO :0046872 and metal ion binding and molecular function this GO :0047391 and alkylglycerophosphoethanolamine phosphodiesterase activity and molecular function this GO :0090305 and nucleic acid phosphodiester bond hydrolysis and biological process, this GO :0003676 : nucleic acid binding, this GO :0003676 : nucleic acid binding and also this GO :0003824 : catalytic activity and also this GO :0004528 : phosphodiesterase I activity and also this GO :0004551 : nucleotide diphosphatase activity and also this GO :0004622 : lysophospholipase activity and also this GO :0005044 : scavenger receptor activity and also this GO :0005509 : calcium ion binding and also this GO :0008134 : transcription factor binding and also this GO :0008270 : zinc ion binding and also this GO :0016787 : hydrolase activity and also this GO :0030247 : polysaccharide binding and also this GO :0046872 : metal ion binding and also this GO :0047391 : alkylglycerophosphoethanolamine phosphodiesterase activity, this GO :0003824 : catalytic activity, this GO :0004528 : phosphodiesterase I activity, this GO :0004551 : nucleotide diphosphatase activity, this GO :0004622 : lysophospholipase activity, this GO :0005044 : scavenger receptor activity, this GO :0005509 : calcium ion binding, this GO :0008134 : transcription factor binding, this GO :0008270 : zinc ion binding, this GO :0016787 : hydrolase activity, this GO :0030247 : polysaccharide binding, this GO :0046872 : metal ion binding, this GO :0047391 : alkylglycerophosphoethanolamine phosphodiesterase activity, ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| Identity: |
3357 |
| Gene: |
ENPP2 |
More about : ENPP2 |
| Long gene name: |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| Synonyms gene: |
PDNP2 |
| Synonyms name: |
autotaxin |
| Locus: |
8q24, 12 |
| Discovery year: |
1995-08-10 |
| GenBank acession: |
D45421 |
| Entrez gene record: |
5168 |
| Pubmed identfication: |
8586446 |
| Havana BLAST/BLAT: |
OTTHUMG00000164995 |