| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
EMP2 |
| Specificity: |
This antibody reacts specifically with EMP2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human EMP2 |
| Gene ID: |
2013 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
EMP-2 is expressed in heart, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium, In adult tissues, Localized to lipid raft domains in the plasma membrane, Overexpression of EMP-2 is associated with endometrial adenocarcinoma, Specifically, as well as Integrins and caveolin-1, brain and liver, lung, ovary and intestine, suggesting a possible role for EMP-2 in tumorigenesis, while fetal expression is highest in kidney, EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
XMP |
| Also known as: |
EMP2 Polyclonal Antibody |
| Other name: |
Anti-EMP2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
EMP2 |
| Short name: |
Anti-EMP2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-EMP2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
3334 |
| Gene: |
EMP2 |
More about : EMP2 |
| Long gene name: |
epithelial membrane protein 2 |
| Locus: |
16p13, 13 |
| Discovery year: |
1997-12-05 |
| GenBank acession: |
U52100 |
| Entrez gene record: |
2013 |
| Pubmed identfication: |
8996089 10331954 16216233 |
| RefSeq identity: |
NM_001424 |
| Havana BLAST/BLAT: |
OTTHUMG00000129752 |