| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NRG3 |
| Specificity: |
This antibody reacts specifically with NRG3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NRG3 |
| Gene ID: |
10718 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor, Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors, May be a survival factor for oligodendrocytes, Direct ligand for the ERBB4 tyrosine kinase receptor |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
NRG3 Polyclonal Antibody |
| Other name: |
Anti-NRG3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NRG3 |
| Short name: |
Anti-NRG3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-neuregulin 3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Extracellular, HRG3 and pro-NRG3, NRG3 and IDBG-631178 and ENSBTAG00000009587 and 539977, NRG3 and IDBG-80642 and ENSG00000185737 and 10718, Nrg3 and IDBG-151248 and ENSMUSG00000041014 and 18183, receptor tyrosine kinase binding, this GO :0001558 and regulation of cell growth and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007171 and activation of transmembrane receptor protein tyrosine kinase activity and biological process this GO :0007389 and pattern specification process and biological process this GO :0008083 and growth factor activity and molecular function this GO :0009790 and embryo development and biological process this GO :0030297 and transmembrane receptor protein tyrosine kinase activator activity and molecular function this GO :0030879 and mammary gland development and biological process this GO :0030971 and receptor tyrosine kinase binding and molecular function this GO :0035556 and intracellular signal transduction and biological process this GO :0060596 and mammary placode formation and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0030297 : transmembrane receptor protein tyrosine kinase activator activity and also this GO :0030971 : receptor tyrosine kinase binding, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0030297 : transmembrane receptor protein tyrosine kinase activator activity, this GO :0030971 : receptor tyrosine kinase binding, neuregulin 3 |
| Identity: |
7999 |
| Gene: |
NRG3 |
More about : NRG3 |
| Long gene name: |
neuregulin 3 |
| Locus: |
10q23, 1 |
| Discovery year: |
1999-03-19 |
| GenBank acession: |
AK098823 |
| Entrez gene record: |
10718 |
| Pubmed identfication: |
9275162 |
| RefSeq identity: |
XM_166086 |
| Havana BLAST/BLAT: |
OTTHUMG00000018626 |