| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Rab11 |
| Specificity: |
This antibody reacts specifically with Rab11 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Rab11 |
| Gene ID: |
8766 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Located on the cytoplasmic face of organelles and vesicles, Rab proteins, Rab11a and Rab11b are known markers for protein trafficking, Rab11a is ubiquitously expressed, The Rab11 proteins are enriched in recycling endosomes and the trans-Golgi network, There are over 40 Rab proteins in mammals, Three membrane proteins, and recycling in the endosomal pathway, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP, help to mediate vesicle docking and fusion, in coordination with the core fusion machinery and Munc-18, rab proteins are involved in intracellular membrane fusion reactions, sorting, synaptobrevin, synaptosomal associated protein of 25 kDa (SNAP-25), where they regulate membrane recycling back to the plasma membrane, while Rab11b is expressed mainly in the heart and brain, Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GAF1 KIAA0857 RIP11 pp75 |
| Also known as: |
Rab11 Polyclonal Antibody |
| Other name: |
Anti-Rab11 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Rab11 |
| Short name: |
Anti-Rab11 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Rab11 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
24845 |
| Gene: |
RAB11FIP5 |
More about : RAB11FIP5 |
| Long gene name: |
RAB11 family interacting protein 5 |
| Synonyms gene name: |
RAB11 family interacting protein 5 (class I) |
| Locus: |
2p13, 2 |
| Discovery year: |
2004-07-22 |
| GenBank acession: |
AF334812 |
| Entrez gene record: |
26056 |
| Pubmed identfication: |
10048485 11163216 |
| RefSeq identity: |
NM_015470 |
| Classification: |
C2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000129779 |