| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NBL1 |
| Specificity: |
This antibody reacts specifically with NBL1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NBL1/DAND1 |
| Gene ID: |
4681 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It is a member of a class of glycoproteins shown to be secreted inhibitors of the transforming growth factor-beta (TGF-beta) and bone morphogenic protein pathways, NBL1 is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, suppression of tumorigenicity 1) is a candidate tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules, NBL1 (Neuroblastoma |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
D1S1733E NB DAN NO3 DAND1 |
| Also known as: |
NBL1 Polyclonal Antibody |
| Other name: |
Anti-NBL1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NBL1 |
| Short name: |
Anti-NBL1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NBL1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
7650 |
| Gene: |
NBL1 |
More about : NBL1 |
| Long gene name: |
DAN family BMP antagonist , neuroblastoma 1 |
| Synonyms gene name: |
neuroblastoma, suppression of tumorigenicity 1 |
| Synonyms name: |
neuroblastoma candidate region, suppression of tumorigenicity 1 neuroblastoma suppressor of tumorigenicity 1 differential screening-selected gene aberrant in neuroblastoma |
| Locus: |
1p36, 13 |
| Discovery year: |
1997-11-20 |
| Entrez gene record: |
4681 |
| Pubmed identfication: |
7633401 |
| RefSeq identity: |
NM_005380 |
| Classification: |
DAN family |
| Havana BLAST/BLAT: |
OTTHUMG00000002700 |