| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CPEB1 |
| Specificity: |
This antibody reacts specifically with CPEB1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CPEB1 |
| Gene ID: |
64506 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Binds to the cytoplasmic polyadenylation element (CPE), In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA, Induces the assembly of stress granules in the absence of stress, Involved in the transport of CPE-containing mRNA to dendrites, Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation (By similarity), a repression that is relieved by phosphorylation or degradation (By similarity), an uridine-rich sequence element (consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR, early development and at postsynapse sites of neurons, those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses (By similarity), Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ13203 CPEB |
| Also known as: |
CPEB1 Polyclonal Antibody |
| Other name: |
Anti-CPEB1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CPEB1 |
| Short name: |
Anti-CPEB1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-CPEB1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
21744 |
| Gene: |
CPEB1 |
More about : CPEB1 |
| Long gene name: |
cytoplasmic polyadenylation element binding protein 1 |
| Locus: |
15q25, 2 |
| Discovery year: |
2003-07-22 |
| GenBank acession: |
AF329402 |
| Entrez gene record: |
64506 |
| Pubmed identfication: |
11223249 |
| RefSeq identity: |
NM_030594 |
| Havana BLAST/BLAT: |
OTTHUMG00000172877 |