| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
HELLS |
| Specificity: |
This antibody reacts specifically with HELLS |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human SMARCA6/HELLS |
| Gene ID: |
3070 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Other helicases function in processes involving DNA strand separation, This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis, and transcription, including replication, recombination, repair, SMARCA6 gene encodes a lymphoid-specific helicase |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PASG SMARCA6 LSH Nbla10143 |
| Also known as: |
HELLS Polyclonal Antibody |
| Other name: |
Anti-HELLS Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
HELLS |
| Short name: |
Anti-HELLS (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, lymphoid-specific (polyclonal), antibody to-helicase |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0008152 and metabolic process and biological process this GO :0010216 and maintenance of DNA methylation and biological process this GO :0016787 and hydrolase activity and molecular function this GO :0031508 and centromeric heterochromatin assembly and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046651 and lymphocyte proliferation and biological process this GO :2001243 and negative regulation of intrinsic apoptotic signaling pathway and biological process, HELLS and IDBG-637847 and ENSBTAG00000005979 and 540933, HELLS and IDBG-83141 and ENSG00000119969 and 3070, Hells and IDBG-163438 and ENSMUSG00000025001 and 15201, LSH and PASG and SMARCA6, centromeric region and cellular component this GO :0001655 and urogenital system development and biological process this GO :0003676 and nucleic acid binding and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0004386 and helicase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005721 and centromeric heterochromatin and cellular component this GO :0006306 and DNA methylation and biological process this GO :0006342 and chromatin silencing and biological process this GO :0006346 and methylation-dependent chromatin silencing and biological process this GO :0006351 and transcription, hydrolase activity, lymphoid-specific, nuclei, this GO :0000775 and chromosome, this GO :0003676 : nucleic acid binding, this GO :0003676 : nucleic acid binding and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0004386 : helicase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016787 : hydrolase activity, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0004386 : helicase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016787 : hydrolase activity, helicase |
| Identity: |
4861 |
| Gene: |
HELLS |
More about : HELLS |
| Long gene name: |
helicase, lymphoid-specific |
| Synonyms name: |
SWI/SNF2-related, actin-dependent regulator of chromatin, matrix-associated, member 6 proliferation-associated SNF2-like protein , subfamily A |
| Locus: |
10q23, 33 |
| Discovery year: |
1998-07-15 |
| GenBank acession: |
AF155827 |
| Entrez gene record: |
3070 |
| Pubmed identfication: |
9878251 10910076 |
| RefSeq identity: |
NM_018063 |
| Classification: |
DNA helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000018793 |