| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GADD45B |
| Specificity: |
This antibody reacts specifically with GADD45B |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GADD45B |
| Gene ID: |
4616 |
| Swiss Prot: |
O75293 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK, Involved in the regulation of growth and apoptosis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GADD45BETA DKFZP566B133 |
| Also known as: |
GADD45B Polyclonal Antibody |
| Other name: |
Anti-GADD45B Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GADD45B |
| Short name: |
Anti-GADD45B (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, b (polyclonal), antibody to-growth arrest and Desoxyribonucleic acid-damage-inducible |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
GADD45B and IDBG-16168 and ENSG00000099860 and 4616, GADD45B and IDBG-644512 and ENSBTAG00000025462 and 618405, GADD45BETA and MYD118, Gadd45b and IDBG-176557 and ENSMUSG00000015312 and 17873, beta, nuclei, protein binding, this GO :0000185 and activation of MAPKKK activity and biological process this GO :0000186 and activation of MAPKK activity and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006915 and apoptotic process and biological process this GO :0006950 and response to stress and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0030154 and cell differentiation and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :1900745 and positive regulation of p38MAPK cascade and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, growth arrest and DNA-damage-inducible |
| Identity: |
4096 |
| Gene: |
GADD45B |
More about : GADD45B |
| Long gene name: |
growth arrest and DNA damage inducible beta |
| Synonyms gene: |
MYD118 |
| Synonyms gene name: |
beta , growth arrest and DNA-damage-inducible |
| Synonyms name: |
myeloid differentiation primary response growth arrest and DNA-damage-inducible beta |
| Locus: |
19p13, 3 |
| Discovery year: |
1994-01-10 |
| GenBank acession: |
AF090950 |
| Entrez gene record: |
4616 |
| Pubmed identfication: |
1899477 9827804 |
| RefSeq identity: |
NM_015675 |
| Havana BLAST/BLAT: |
OTTHUMG00000180434 |