| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NAIP |
| Specificity: |
This antibody reacts specifically with NAIP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NAIP |
| Gene ID: |
4671 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy, Prevents motor-neuron apoptosis induced by a variety of signals |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NLRB1 |
| Also known as: |
NAIP Polyclonal Antibody |
| Other name: |
Anti-NAIP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NAIP |
| Short name: |
Anti-NAIP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, apoptosis inhibitory protein (polyclonal), antibody to-NLR family |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BIRC1 and NLRB1 and psiNAIP, NAIP and IDBG-402309 and ENSG00000249437 and 4671, NAIP and IDBG-628641 and ENSBTAG00000003326 and 539780, Plasma membranes, apoptosis inhibitory protein, metal ion binding, this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007399 and nervous system development and biological process this GO :0008152 and metabolic process and biological process this GO :0016323 and basolateral plasma membrane and cellular component this GO :0017111 and nucleoside-triphosphatase activity and molecular function this GO :0043027 and cysteine-type endopeptidase inhibitor activity involved in apoptotic process and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0046872 and metal ion binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0017111 : nucleoside-triphosphatase activity and also this GO :0043027 : cysteine-type endopeptidase inhibitor activity involved in apoptotic process and also this GO :0046872 : metal ion binding, this GO :0005524 : ATP binding, this GO :0017111 : nucleoside-triphosphatase activity, this GO :0043027 : cysteine-type endopeptidase inhibitor activity involved in apoptotic process, this GO :0046872 : metal ion binding, NLR family |
| Identity: |
7634 |
| Gene: |
NAIP |
More about : NAIP |
| Long gene name: |
NLR family apoptosis inhibitory protein |
| Synonyms gene: |
BIRC1 |
| Synonyms gene name: |
baculoviral IAP repeat-containing 1 |
| Synonyms name: |
BIR domain containing 1 , leucine rich repeat and BIR domain containing 1 NLR family, nucleotide-binding oligomerization domain |
| Locus: |
5q13, 2 |
| Discovery year: |
1998-05-14 |
| GenBank acession: |
U19251 |
| Entrez gene record: |
4671 |
| Pubmed identfication: |
7813013 |
| RefSeq identity: |
NM_004536 |
| Classification: |
Baculoviral IAP repeat containing NLR family |
| Havana BLAST/BLAT: |
OTTHUMG00000163318 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |