| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PTPN7 Ser246 |
| Specificity: |
This antibody reacts specifically with PTPN7 (Ser246) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser246 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from mouse PTPN7 around the phosphorylation site of Ser246 |
| Gene ID: |
5778 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus), Mouse (Mus musculus) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Multiple alternatively spliced transcript variants have been found for this gene, PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities, This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, This gene is preferentially expressed in a variety of hematopoietic cells, [provided by RefSeq], and is an early response gene in lymphokine stimulated cells, and oncogenic transformation, differentiation, mitotic cycle, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway, The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HEPTP LC-PTP |
| Also known as: |
PTPN7 (Ser246) Polyclonal Antibody |
| Other name: |
Anti-PTPN7 (Ser246) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PTPN7 (Ser246) |
| Short name: |
Anti-PTPN7 (Ser246) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PTPN7 (Ser246) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9659 |
| Gene: |
PTPN7 |
More about : PTPN7 |
| Long gene name: |
non-receptor type 7 , protein tyrosine phosphatase |
| Locus: |
1q32, 1 |
| Discovery year: |
1993-03-03 |
| GenBank acession: |
BC001746 |
| Entrez gene record: |
5778 |
| Pubmed identfication: |
1510684 |
| RefSeq identity: |
NM_002832 |
| Classification: |
Protein tyrosine phosphatases, non-receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000035931 |