| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MAX protein Tyr123 |
| Specificity: |
This antibody reacts specifically with MAX protein(Tyr123) |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr123 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human MAX protein around the phosphorylation site of Tyr123 |
| Gene ID: |
4149 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A pseudogene of this gene is located on the long arm of chromosome 7, Alternative splicing results in multiple transcript variants, It is able to form homodimers and heterodimers with other family members, Mutations of this gene have been reported to be associated with hereditary pheochromocytoma, Mxi1 and Myc, Myc is an oncoprotein implicated in cell proliferation, The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation, differentiation and apoptosis, which include Mad, MAX protein is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
bHLHd4 bHLHd5 bHLHd6 bHLHd7 bHLHd8 |
| Also known as: |
MAX protein(Tyr123) Polyclonal Antibody |
| Other name: |
Anti-MAX protein(Tyr123) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MAX protein(Tyr123) |
| Short name: |
Anti-MAX protein(Tyr123) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-MYC associated factor X protein(Tyr123) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006461 and protein complex assembly and biological process this GO :0009267 and cellular response to starvation and biological process this GO :0010243 and response to organonitrogen compound and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0016605 and PML body and cellular component this GO :0030425 and dendrite and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0032868 and response to insulin and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048678 and response to axon injury and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0071339 and MLL1 complex and cellular component this GO :0071375 and cellular response to peptide hormone stimulus and biological process, MAX and IDBG-646780 and ENSBTAG00000017994 and 540616, MAX and IDBG-9524 and ENSG00000125952 and 4149, Max and IDBG-151490 and ENSMUSG00000059436 and 17187, bHLHd4, nuclei, protein dimerization activity, this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003712 and transcription cofactor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006355 and regulation of transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003712 : transcription cofactor activity and also this GO :0003713 : transcription coactivator activity and also this GO :0005515 : protein binding and also this GO :0032403 : protein complex binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0046983 : protein dimerization activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003712 : transcription cofactor activity, this GO :0003713 : transcription coactivator activity, this GO :0005515 : protein binding, this GO :0032403 : protein complex binding, this GO :0042803 : protein homodimerization activity, this GO :0043565 : sequence-specific DNA binding, this GO :0046982 : protein heterodimerization activity, this GO :0046983 : protein dimerization activity, MYC associated factor X |
| Identity: |
6913 |
| Gene: |
MAX |
More about : MAX |
| Long gene name: |
MYC associated factor X |
| Synonyms gene name: |
MAX protein |
| Locus: |
14q23, 3 |
| Discovery year: |
1992-10-27 |
| Entrez gene record: |
4149 |
| Pubmed identfication: |
1557420 |
| RefSeq identity: |
NM_197957 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000142809 |
| Locus Specific Databases: |
LRG_530 |