| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GABBR1 Ser923 |
| Specificity: |
This antibody reacts specifically with GABBR1 (Ser923) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser923 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from mouse GABBR1 around the phosphorylation site of Ser923 |
| Gene ID: |
54393 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternative splicing of this gene generates multiple transcript variants, GABA exerts its effects through ionotropic [GABA(A/C)] receptors, GABA(B) receptor 1 and GABA(B) receptor 2, Jun 2009], Susceptibility loci for multiple sclerosis, The GABA(B) receptor 1 gene is mapped to chromosome 6p21, The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, [provided by RefSeq, and metabotropic [GABA(B)] receptors, and schizophrenia have also been mapped in this region, epilepsy, prolonged inhibitory signals, to produce fast synaptic inhibition, to produce slow, 3 within the HLA class I region close to the HLA-F gene, Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
hGB1a GPRC3A |
| Also known as: |
GABBR1 (Ser923) Polyclonal Antibody |
| Other name: |
Anti-GABBR1 (Ser923) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GABBR1 (Ser923) |
| Short name: |
Anti-GABBR1 (Ser923) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-GABBR1 (Ser923) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
4070 |
| Gene: |
GABBR1 |
More about : GABBR1 |
| Long gene name: |
gamma-aminobutyric acid type B receptor subunit 1 |
| Synonyms gene name: |
1 , gamma-aminobutyric acid (GABA) B receptor |
| Synonyms name: |
GABA-B receptor |
| Locus: |
6p22, 1 |
| Discovery year: |
1998-04-21 |
| GenBank acession: |
Y11044 |
| Entrez gene record: |
2550 |
| Pubmed identfication: |
9753614 9798068 |
| Classification: |
Gamma-aminobutyric acid type B receptor subunits Sushi domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031095 |