| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
BRIP1 Ser990 |
| Specificity: |
BRIP1 (Ser990), This phosphorylation site is homologous to that of Ser921 in Bovine |
| Modification: |
Phosphorylation |
| Modification site: |
Ser990 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human BRIP1 around the phosphorylation site of Ser990 |
| Gene ID: |
83990 |
| Swiss Prot: |
Q9BX63 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts late in the Fanconi anemia pathway, Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1, after FANCD2 ubiquitination, DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
OF BACH1 FANCJ |
| Also known as: |
BRIP1 (Ser990) Polyclonal Antibody |
| Other name: |
Anti-BRIP1 (Ser990) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
BRIP1 (Ser990) |
| Short name: |
Anti-BRIP1 (Ser990) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-BRIP1 (Ser990) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
20473 |
| Gene: |
BRIP1 |
More about : BRIP1 |
| Long gene name: |
BRCA1 interacting protein C-terminal helicase 1 |
| Synonyms name: |
BRCA1/BRCA2-associated helicase 1 |
| Locus: |
17q23, 2 |
| Discovery year: |
2003-04-11 |
| GenBank acession: |
AF360549 |
| Entrez gene record: |
83990 |
| Pubmed identfication: |
11595410 11301010 |
| RefSeq identity: |
NM_032043 |
| Classification: |
DNA helicases BRCA1 B complex Fanconi anemia complementation groups |
| Havana BLAST/BLAT: |
OTTHUMG00000179233 |
| Locus Specific Databases: |
Fanconi Anaemia Mutation Database Fanconi anemia database LRG_300 |