| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ATF4 Ser245 |
| Specificity: |
This antibody reacts specifically with ATF4 (Ser245) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser245 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human ATF4 around the phosphorylation site of Ser245 |
| Gene ID: |
468 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB2), The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP1 family of transcription factors, These transcription factors share a leucine zipper region that is involved in protein-protein interactions, cAMP-response element binding proteins (CREBs) and CREB-like proteins, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain (referenced from Entrez gene), ATF4 is a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
TAXREB67 CREB-2 |
| Also known as: |
ATF4 (Ser245) Polyclonal Antibody |
| Other name: |
Anti-ATF4 (Ser245) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ATF4 (Ser245) |
| Short name: |
Anti-ATF4 (Ser245) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ATF4 (Ser245) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
786 |
| Gene: |
ATF4 |
More about : ATF4 |
| Long gene name: |
activating transcription factor 4 |
| Synonyms gene: |
TXREB |
| Synonyms gene name: |
activating transcription factor 4 (tax-responsive enhancer element B67) |
| Synonyms name: |
tax-responsive enhancer element B67 |
| Locus: |
22q13, 1 |
| Discovery year: |
1992-06-09 |
| GenBank acession: |
D90209 |
| Entrez gene record: |
468 |
| Pubmed identfication: |
1847461 1534408 |
| RefSeq identity: |
NM_001675 |
| Classification: |
Basic leucine zipper proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000151099 |