| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Alpha Dystroglycan |
| Specificity: |
This antibody reacts specifically with Alpha Dystroglycan |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DAG1 |
| Gene ID: |
1605 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternative splicing results in multiple transcript variants all encoding the same protein, Apr 2010], Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies, Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane, The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence, rendering muscle fibers more susceptible to necrosis, Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix, [provided by RefSeq |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
156DAG, A3a, Alpha-DG, Beta-DG, Beta-dystroglycan, DAG, DAG1_HUMAN, Dag1, Dystroglycan, Dystroglycan 1 dystrophin-associated glycoprotein 1, Dystrophin-associated glycoprotein 1, Dystrophin-associated glycoprotein 1, beta Dystroglycan, AGRNR |
| Also known as: |
Alpha Dystroglycan Polyclonal Antibody |
| Other name: |
Anti-Alpha Dystroglycan Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Description: |
- or alpha protein sometimes glycoprotein present in blood, The Anti-Alpha Dystroglycan (Polyclonal) Fluor 594 is a &alpha |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Alpha Dystroglycan |
| Short name: |
Anti-Alpha Dystroglycan (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-a Dystroglycan (polyclonal) |
| Alternative technique: |
polyclonals |