| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GLO1 |
| Specificity: |
This antibody reacts specifically with GLO1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GLO1 |
| Gene ID: |
2739 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
GLO is linked to HLA and is localized to 6p21, between HLA and the centromere, 1, 3-p21, The enzyme encoded by GLO1 is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
GLOD1 |
| Also known as: |
GLO1 Polyclonal Antibody |
| Other name: |
Anti-GLO1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GLO1 |
| Short name: |
Anti-GLO1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-glyoxalase I (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cytoplasm, GLO1 and IDBG-630387 and ENSBTAG00000012703 and 101905254, GLO1 and IDBG-85868 and ENSG00000124767 and 2739, GLOD1 and GLYI and HEL-S-74, Glo1 and IDBG-161603 and ENSMUSG00000024026 and 109801, metal ion binding, this GO :0004462 and lactoylglutathione lyase activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006749 and glutathione metabolic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009438 and methylglyoxal metabolic process and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0046872 and metal ion binding and molecular function this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004462 : lactoylglutathione lyase activity, this GO :0004462 : lactoylglutathione lyase activity and also this GO :0008270 : zinc ion binding and also this GO :0046872 : metal ion binding, this GO :0008270 : zinc ion binding, this GO :0046872 : metal ion binding, 540335, glyoxalase I |
| Identity: |
4323 |
| Gene: |
GLO1 |
More about : GLO1 |
| Long gene name: |
glyoxalase I |
| Synonyms name: |
glyoxalase domain containing 1 |
| Locus: |
6p21, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
L07837 |
| Entrez gene record: |
2739 |
| Pubmed identfication: |
8449929 7684374 |
| RefSeq identity: |
NM_006708 |
| Havana BLAST/BLAT: |
OTTHUMG00000014636 |