| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
OSMR |
| Specificity: |
This antibody reacts specifically with OSMR |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Oncostatin-M receptor |
| Gene ID: |
157869 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily, Many IL6 cytokines utilize gp130 as a common receptor subunit, OSM binds to the gp130 receptor subunit and, OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells, Oncostatin M is a member of the IL6 family of cytokines |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
OSMRB |
| Also known as: |
OSMR Polyclonal Antibody |
| Other name: |
Anti-OSMR Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
OSMR |
| Short name: |
Anti-OSMR (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-oncostatin M receptor (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BT, OSMR and IDBG-17615 and ENSG00000145623 and 9180, OSMRB and PLCA1, Osmr and IDBG-128241 and ENSMUSG00000022146 and 18414, growth factor binding, multiple, this GO :0002675 and positive regulation of acute inflammatory response and biological process this GO :0004924 and oncostatin-M receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005900 and oncostatin-M receptor complex and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0019838 and growth factor binding and molecular function this GO :0034097 and response to cytokine and biological process this GO :0038165 and oncostatin-M-mediated signaling pathway and biological process, this GO :0004924 : oncostatin-M receptor activity, this GO :0004924 : oncostatin-M receptor activity and also this GO :0005515 : protein binding and also this GO :0019838 : growth factor binding, this GO :0005515 : protein binding, this GO :0019838 : growth factor binding, 103407 and IDBG-629972 and ENSBTAG00000033107 and 514720, oncostatin M receptor |
| Identity: |
8507 |
| Gene: |
OSMR |
More about : OSMR |
| Long gene name: |
oncostatin M receptor |
| Locus: |
5p13, 1 |
| Discovery year: |
1999-02-17 |
| GenBank acession: |
U60805 |
| Entrez gene record: |
9180 |
| Pubmed identfication: |
8999038 |
| RefSeq identity: |
NM_003999 |
| Classification: |
Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000090811 |