| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PFKFB1 |
| Specificity: |
This antibody reacts specifically with PFKFB1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PFKFB1 |
| Gene ID: |
5207 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It forms a homodimer that is involved in both the synthesis and degradation of fructose 2, The activity of this enzyme is thought to regulate glucose homeostasis, 6-biphosphatase enzymes, 6-bisphosphate, PFKFB1 belongs to the family of bifunctional 6-phosphofructo-2-kinase:fructose-2 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
PFKFB1 Polyclonal Antibody |
| Other name: |
Anti-PFKFB1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PFKFB1 |
| Short name: |
Anti-PFKFB1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, 6-biphosphatase 1 (polyclonal), antibody to-phosphofructo-2-kinase/fructose-2 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Cytoplasm, F6PK and HL2K and PFRX, PFKFB1 and IDBG-637557 and ENSBTAG00000000172 and 282304, PFKFB1 and IDBG-71927 and ENSG00000158571 and 5207, Pfkfb1 and IDBG-178179 and ENSMUSG00000025271 and 18639, fructose-2, this GO :0003873 and 6-phosphofructo-2-kinase activity and molecular function this GO :0004331 and fructose-2, this GO :0003873 : 6-phosphofructo-2-kinase activity, this GO :0003873 : 6-phosphofructo-2-kinase activity and also this GO :0004331 : fructose-2, this GO :0004331 : fructose-2, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0019900 : kinase binding, this GO :0042802 : identical protein binding, this GO :0070095 : fructose-6-phosphate binding, 6-biphosphatase 1, 6-biphosphatase complex and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0046835 and carbohydrate phosphorylation and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0051591 and response to cAMP and biological process this GO :0070095 and fructose-6-phosphate binding and molecular function, 6-bisphosphate 2-phosphatase activity, 6-bisphosphate 2-phosphatase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0019900 : kinase binding and also this GO :0042802 : identical protein binding and also this GO :0070095 : fructose-6-phosphate binding, 6-bisphosphate 2-phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0006000 and fructose metabolic process and biological process this GO :0006003 and fructose 2, 6-bisphosphate metabolic process and biological process this GO :0006006 and glucose metabolic process and biological process this GO :0006094 and gluconeogenesis and biological process this GO :0006096 and glycolytic process and biological process this GO :0006112 and energy reserve metabolic process and biological process this GO :0016301 and kinase activity and molecular function this GO :0016311 and dephosphorylation and biological process this GO :0019900 and kinase binding and molecular function this GO :0031100 and organ regeneration and biological process this GO :0032868 and response to insulin and biological process this GO :0033133 and positive regulation of glucokinase activity and biological process this GO :0033762 and response to gluca this GO n and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042594 and response to starvation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043540 and 6-phosphofructo-2-kinase/fructose-2, 6-phosphofructo-2-kinase/fructose-2 |
| Identity: |
8872 |
| Gene: |
PFKFB1 |
More about : PFKFB1 |
| Long gene name: |
6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1 |
| Synonyms gene: |
PFRX |
| Locus: |
Xp11, 21 |
| Discovery year: |
1990-09-10 |
| Entrez gene record: |
5207 |
| Pubmed identfication: |
9119406 |
| Classification: |
6-phosphofructo-2-kinases/fructose-2, 6-biphosphatases |
| Havana BLAST/BLAT: |
OTTHUMG00000021643 |
| Locus Specific Databases: |
Mental Retardation database |