| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CRTAM |
| Specificity: |
This antibody reacts specifically with CRTAM |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CRTAM |
| Gene ID: |
56253 |
| Swiss Prot: |
O95727 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD355 |
| Also known as: |
CRTAM Polyclonal Antibody |
| Other name: |
Anti-CRTAM Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CRTAM |
| Short name: |
Anti-CRTAM (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-cytotoxic and regulatory T cellular molecule (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
CRTAM and IDBG-632232 and ENSBTAG00000005193 and 781864, CRTAM and IDBG-74801 and ENSG00000109943 and 56253, Crtam and IDBG-153804 and ENSMUSG00000032021 and 54698, Plasma membranes, protein binding, this GO :0002355 and detection of tumor cell and biological process this GO :0002860 and positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0008037 and cell recognition and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0045954 and positive regulation of natural killer cell mediated cytotoxicity and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process this GO :0050776 and regulation of immune response and biological process this GO :0051606 and detection of stimulus and biological process, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, cytotoxic and regulatory T cell molecule |
| Identity: |
24313 |
| Gene: |
CRTAM |
More about : CRTAM |
| Long gene name: |
cytotoxic and regulatory T-cell molecule |
| Synonyms gene name: |
cytotoxic and regulatory T cell molecule |
| Synonyms name: |
class I MHC restricted T cell associated molecule |
| Locus: |
11q24, 1 |
| Discovery year: |
2006-06-27 |
| GenBank acession: |
AF001622 |
| Entrez gene record: |
56253 |
| Pubmed identfication: |
10811014 16300832 |
| RefSeq identity: |
NM_019604 |
| Classification: |
C2-set domain containing CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166026 |