| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
MPO |
| Specificity: |
This antibody reacts specifically with MPO |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Lysosome |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human MPO |
| Gene ID: |
4353 |
| Swiss Prot: |
P05164 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In the stimulated PMN, It is responsible for microbicidal activity against a wide range of organisms, MPO catalyzes the production of hypohalous acids, and other toxic intermediates that greatly enhance PMN microbicidal activity, primarily hypochlorous acid in physiologic situations, Part of the host defense system of polymorphonuclear leukocytes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
MPO Polyclonal Antibody |
| Other name: |
Anti-MPO Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
MPO |
| Short name: |
Anti-MPO (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-myeloperoxidase (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
MPO and IDBG-60932 and ENSG00000005381 and 4353, MPO and IDBG-629390 and ENSBTAG00000011616 and 511206, Mpo and IDBG-207719 and ENSMUSG00000009350 and 17523, metal ion binding, nuclei, this GO :0001878 and response to yeast and biological process this GO :0002149 and hypochlorous acid biosynthetic process and biological process this GO :0002679 and respiratory burst involved in defense response and biological process this GO :0003682 and chromatin binding and molecular function this GO :0004601 and peroxidase activity and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005764 and lysosome and cellular component this GO :0006952 and defense response and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007568 and aging and biological process this GO :0008201 and heparin binding and molecular function this GO :0009612 and response to mechanical stimulus and biological process this GO :0019430 and removal of superoxide radicals and biological process this GO :0020037 and heme binding and molecular function this GO :0030141 and secretory granule and cellular component this GO :0032094 and response to food and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0034374 and low-density lipoprotein particle remodeling and biological process this GO :0042582 and azurophil granule and cellular component this GO :0042744 and hydrogen peroxide catabolic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0044130 and negative regulation of growth of symbiont in host and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050832 and defense response to fungus and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :1990268 and response to this GO ld nanoparticle and biological process, this GO :0003682 : chromatin binding, this GO :0003682 : chromatin binding and also this GO :0004601 : peroxidase activity and also this GO :0008201 : heparin binding and also this GO :0020037 : heme binding and also this GO :0046872 : metal ion binding, this GO :0004601 : peroxidase activity, this GO :0008201 : heparin binding, this GO :0020037 : heme binding, this GO :0046872 : metal ion binding, myeloperoxidase |
| Identity: |
7218 |
| Gene: |
MPO |
More about : MPO |
| Long gene name: |
myeloperoxidase |
| Locus: |
17q22 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
4353 |
| Havana BLAST/BLAT: |
OTTHUMG00000178922 |
| Locus Specific Databases: |
MPObase: Mutation registry for Myeloperoxidase deficiency LRG_84 |