| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Complement C3d fragment |
| Specificity: |
This antibody reacts specifically with Complement C3d fragment |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Complement C3d fragment |
| Gene ID: |
718 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
C3 is a central factor in the complement cascade, C3 is an acute phase protein that is produced by a wide range of tissues, C3g and C3c, Further degradation leads to the formation of the alpha chain products C3d, It is central to the alternative pathway that leads to the C3 convertase C3bBb, The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a, These convertases cleave C3 resulting in C3a and C3b, including renal epithelial cells and hepatocytes, The complement factor C3 consists of an alpha and a beta chain |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CD21 C3DR |
| Also known as: |
Complement C3d fragment Antibody |
| Other name: |
Anti-Complement C3d fragment |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Complement C3d |
| Short name: |
Anti-Complement C3d Fluor 594 |
| Isotype: |
Complement fragments, Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small, IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion, bp DNA fragments are common, coli expressed, single chain variable fragments can be E, Antibody fragments and scFv fragments |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Complement C3d fragment |
| Identity: |
2336 |
| Gene: |
CR2 |
More about : CR2 |
| Long gene name: |
complement C3d receptor 2 |
| Synonyms gene name: |
complement component (3d/Epstein Barr virus) receptor 2 complement component 3d receptor 2 |
| Synonyms name: |
Epstein-Barr virus receptor |
| Locus: |
1q32, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M26004 |
| Entrez gene record: |
1380 |
| RefSeq identity: |
NM_001877 |
| Classification: |
Sushi domain containing Complement system CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000036307 |
| Locus Specific Databases: |
LRG_348 |