| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GDF9 |
| Specificity: |
This antibody reacts specifically with GDF9 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human GDF9 |
| Gene ID: |
2661 |
| Swiss Prot: |
O60383 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B, It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells, It suppresses FST and FSTL3 production in granulosa-lutein cells, Promotes cell transition from G0/G1 to S and G2/M phases, Promotes primordial follicle development, Stimulates granulosa cell proliferation, and RB1 phosphorylation, through an increase of CCND1 and CCNE1 expression, Required for ovarian folliculogenesis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
GDF9 Polyclonal Antibody |
| Other name: |
Anti-GDF9 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GDF9 |
| Short name: |
Anti-GDF9 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-growth differentiation factor 9 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
Extracellular, GDF9 and IDBG-43527 and ENSG00000164404 and 2661, GDF9 and IDBG-645713 and ENSBTAG00000009478 and 282574, Gdf9 and IDBG-171675 and ENSMUSG00000018238 and 14566, growth factor activity, this GO :0001555 and oocyte growth and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007292 and female gamete generation and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :2000870 and regulation of progesterone secretion and biological process, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0008083 : growth factor activity, this GO :0008083 : growth factor activity, growth differentiation factor 9 |
| Identity: |
4224 |
| Gene: |
GDF9 |
More about : GDF9 |
| Long gene name: |
growth differentiation factor 9 |
| Locus: |
5q31, 1 |
| Discovery year: |
1997-09-12 |
| Entrez gene record: |
2661 |
| Pubmed identfication: |
7760846 |
| RefSeq identity: |
NM_005260 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000059842 |