| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
AQP2 |
| Specificity: |
This antibody reacts specifically with AQP2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human AQP2 |
| Gene ID: |
359 |
| Swiss Prot: |
P41181 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
thereby permitting water to move in the direction of an osmotic gradient, Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
AQP2 Polyclonal Antibody |
| Other name: |
Anti-AQP2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
AQP2 |
| Short name: |
Anti-AQP2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-aquaporin 2 (collecting duct) (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
AQP-CD and WCH-CD, AQP2 and IDBG-32089 and ENSG00000167580 and 359, AQP2 and IDBG-632459 and ENSBTAG00000008374 and 539870, Aqp2 and IDBG-183373 and ENSMUSG00000023013 and 11827, PDZ domain binding, Plasma membranes, this GO :0003097 and renal water transport and biological process this GO :0003779 and actin binding and molecular function this GO :0005215 and transporter activity and molecular function this GO :0005372 and water transmembrane transporter activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005764 and lysosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005791 and rough endoplasmic reticulum and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006810 and transport and biological process this GO :0006833 and water transport and biological process this GO :0006884 and cell volume homeostasis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006972 and hyperosmotic response and biological process this GO :0007565 and female pregnancy and biological process this GO :0007568 and aging and biological process this GO :0007588 and excretion and biological process this GO :0009414 and response to water deprivation and biological process this GO :0009651 and response to salt stress and biological process this GO :0009725 and response to hormone and biological process this GO :0010226 and response to lithium ion and biological process this GO :0015168 and glycerol transmembrane transporter activity and molecular function this GO :0015250 and water channel activity and molecular function this GO :0015793 and glycerol transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0030042 and actin filament depolymerization and biological process this GO :0030133 and transport vesicle and cellular component this GO :0030136 and clathrin-coated vesicle and cellular component this GO :0030165 and PDZ domain binding and molecular function this GO :0030658 and transport vesicle membrane and cellular component this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033762 and response to gluca this GO n and biological process this GO :0042594 and response to starvation and biological process this GO :0042631 and cellular response to water deprivation and biological process this GO :0043234 and protein complex and cellular component this GO :0051592 and response to calcium ion and biological process this GO :0051928 and positive regulation of calcium ion transport and biological process this GO :0055037 and recycling endosome and cellular component this GO :0055085 and transmembrane transport and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070382 and exocytic vesicle and cellular component this GO :0071280 and cellular response to copper ion and biological process this GO :0071288 and cellular response to mercury ion and biological process this GO :0072205 and metanephric collecting duct development and biological process, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0005215 : transporter activity and also this GO :0005372 : water transmembrane transporter activity and also this GO :0005515 : protein binding and also this GO :0015168 : glycerol transmembrane transporter activity and also this GO :0015250 : water channel activity and also this GO :0030165 : PDZ domain binding, this GO :0005215 : transporter activity, this GO :0005372 : water transmembrane transporter activity, this GO :0005515 : protein binding, this GO :0015168 : glycerol transmembrane transporter activity, this GO :0015250 : water channel activity, this GO :0030165 : PDZ domain binding, aquaporin 2 (collecting duct) |
| Identity: |
634 |
| Gene: |
AQP2 |
More about : AQP2 |
| Long gene name: |
aquaporin 2 |
| Synonyms gene name: |
aquaporin 2 (collecting duct) |
| Locus: |
12q13, 12 |
| Discovery year: |
1993-07-09 |
| Entrez gene record: |
359 |
| Pubmed identfication: |
7512890 |
| RefSeq identity: |
NM_000486 |
| Classification: |
Aquaporins |
| Havana BLAST/BLAT: |
OTTHUMG00000169709 |
| Locus Specific Databases: |
LRG_717 |