| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
ELAC2 |
| Specificity: |
This antibody reacts specifically with ELAC2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human ELAC2 |
| Gene ID: |
60528 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
A number of allelic variants have been investigated in hereditary prostate cancer, ELAC2 also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), It is thought to be involved in tRNA maturation, Mutations in this gene result in an increased risk of prostate cancer, acting by removing a 3' trailer from precursor tRNA, and reduced expression can suppress transforming growth factor-beta induced growth arrest, ELAC2 is a zinc phosphodiesterase which displays some tRNA 3' processing endonuclease activity |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLJ10530 HPC2 |
| Also known as: |
ELAC2 Polyclonal Antibody |
| Other name: |
Anti-ELAC2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
ELAC2 |
| Short name: |
Anti-ELAC2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-ELAC2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14198 |
| Gene: |
ELAC2 |
More about : ELAC2 |
| Long gene name: |
elaC ribonuclease Z 2 |
| Synonyms gene name: |
coli) , coli) homolog 2 elaC homolog 2 (E, elaC (E |
| Synonyms name: |
tRNase Z (long form) |
| Locus: |
17p12 |
| Discovery year: |
2000-12-14 |
| GenBank acession: |
AF304370 |
| Entrez gene record: |
60528 |
| Pubmed identfication: |
10986046 16636667 21559454 |
| Havana BLAST/BLAT: |
OTTHUMG00000058764 |