| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DDIT4 |
| Specificity: |
This antibody reacts specifically with DDIT4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DDIT4 |
| Gene ID: |
54541 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Promotes neuronal cell death, Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1 |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
RTP801 FLJ20500 REDD-1 REDD1 Dig2 |
| Also known as: |
DDIT4 Polyclonal Antibody |
| Other name: |
Anti-DDIT4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DDIT4 |
| Short name: |
Anti-DDIT4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Desoxyribonucleic acid-damage-inducible transcript 4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
14-3-3 protein binding, Cytoplasm, DDIT4 and IDBG-629952 and ENSBTAG00000000163 and 529235, DDIT4 and IDBG-77884 and ENSG00000168209 and 54541, Ddit4 and IDBG-154242 and ENSMUSG00000020108 and 74747, this GO :0001666 and response to hypoxia and biological process this GO :0001764 and neuron migration and biological process this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0007420 and brain development and biological process this GO :0008283 and cell proliferation and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0010801 and negative regulation of peptidyl-threonine phosphorylation and biological process this GO :0030182 and neuron differentiation and biological process this GO :0032007 and negative regulation of TOR signaling and biological process this GO :0033137 and negative regulation of peptidyl-serine phosphorylation and biological process this GO :0042771 and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator and biological process this GO :0043241 and protein complex disassembly and biological process this GO :0045820 and negative regulation of glycolytic process and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051607 and defense response to virus and biological process this GO :0071889 and 14-3-3 protein binding and molecular function this GO :0072593 and reactive oxygen species metabolic process and biological process this GO :1901216 and positive regulation of neuron death and biological process this GO :1902532 and negative regulation of intracellular signal transduction and biological process, this GO :0071889 : 14-3-3 protein binding, this GO :0071889 : 14-3-3 protein binding, DNA-damage-inducible transcript 4 |
| Identity: |
24944 |
| Gene: |
DDIT4 |
More about : DDIT4 |
| Long gene name: |
DNA damage inducible transcript 4 |
| Synonyms gene name: |
DNA-damage-inducible transcript 4 |
| Synonyms name: |
HIF-1 responsive RTP801 |
| Locus: |
10q22, 1 |
| Discovery year: |
2004-02-12 |
| GenBank acession: |
AK000507 |
| Entrez gene record: |
54541 |
| Pubmed identfication: |
11884613 |
| RefSeq identity: |
NM_019058 |
| Havana BLAST/BLAT: |
OTTHUMG00000183961 |