| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PKMYT1 |
| Specificity: |
This antibody reacts specifically with PKMYT1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human PKMYT1 |
| Gene ID: |
9088 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It may be a downstream target of Notch signaling pathway during eye development, It may be involved in phosphorylation of cdc2 on 'Tyr-15' to a lesser degree, It mediates phosphorylation of cdc2 predominantly on 'Thr-14' and is also involved in Golgi fragmentation, It preferentially phosphorylates and inactivates cell division cycle 2 protein (cdc2), PKMYT1 is negatively regulated by hyperphosphorylation during mitosis, and thus acts as a negative regulator of entry into mitosis (G2 to M transition), however tyrosine kinase activity is unclear and may be indirect, PKMYT1 is a member of the serine/threonine protein kinase family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
MYT1 PPP1R126 |
| Also known as: |
PKMYT1 Polyclonal Antibody |
| Other name: |
Anti-PKMYT1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PKMYT1 |
| Short name: |
Anti-PKMYT1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PKMYT1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
29650 |
| Gene: |
PKMYT1 |
More about : PKMYT1 |
| Long gene name: |
membrane associated tyrosine/threonine 1 , protein kinase |
| Synonyms name: |
membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase protein phosphatase 1, regulatory subunit 126 |
| Locus: |
16p13, 3 |
| Discovery year: |
2005-01-20 |
| GenBank acession: |
AK097642 |
| Entrez gene record: |
9088 |
| Pubmed identfication: |
9001210 12606722 |
| RefSeq identity: |
NM_004203 |
| Classification: |
Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000128975 |