| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NUDEL |
| Specificity: |
This antibody reacts specifically with NUDEL |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NUDEL |
| Gene ID: |
81565 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Immunostaining of embryonic day 18 mouse brain sections revealed staining of migrating neurons and thalamocortical axons of the intermediate zone of the developing cerebral cortex, In fractionated rat brain, It has a coiled coil motif (residues 19 to 201), It is invovled in microtubule organization, Nudel and Lis1 are both found in fractions enriched for postsynaptic density proteins, Nudel shares about 50% identity with mouse and human NUDE proteins, Pafah1b1, Pahfah1b2, The deduced protein contains 345 amino acids and has a calculated molecular mass of 38, Western blot analysis of mouse tissues shows abundant expression of Nudel in brain and testis, and much lower expression in heart, and neuronal positioning in concert with various other factors (including Lis1, and skeletal muscle, as well as several other developing brain regions, dynein, dynorphin A and cdk5), followed by several potential phosphorylation sites for casein kinase II, kidney, liver, nuclear translocation, protein kinase C or CDK5, 4 kDa, Nudel is important for normal cortical development |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
NUDEL MITAP1 NDE1L1 NDE2 |
| Also known as: |
NUDEL Polyclonal Antibody |
| Other name: |
Anti-NUDEL Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NUDEL |
| Short name: |
Anti-NUDEL (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-NUDEL (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17620 |
| Gene: |
NDEL1 |
More about : NDEL1 |
| Long gene name: |
nudE neurodevelopment protein 1 like 1 |
| Synonyms gene name: |
nidulans)-like 1 , nidulans)-like 1 nudE nuclear distribution E homolog (A, nudE nuclear distribution gene E homolog (A |
| Locus: |
17p13, 1 |
| Discovery year: |
2003-04-10 |
| GenBank acession: |
AF182078 |
| Entrez gene record: |
81565 |
| Pubmed identfication: |
11163260 11163259 |
| RefSeq identity: |
NM_030808 |
| Havana BLAST/BLAT: |
OTTHUMG00000108193 |