| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
NDUFS3 |
| Specificity: |
This antibody reacts specifically with NDUFS3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Membrane bound |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human NDUFS3 |
| Gene ID: |
4722 |
| Swiss Prot: |
O75489 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Complex I functions in the transfer of electrons from NADH to the respiratory chain, The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity), Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CI-30 |
| Also known as: |
NDUFS3 Polyclonal Antibody |
| Other name: |
Anti-NDUFS3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
NDUFS3 |
| Short name: |
Anti-NDUFS3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different  |
| Label: |
ALEXA |
| Alternative name: |
30kDa (NADH-coenzyme Q reductase) (polyclonal), ALEXA Fluor 594, antibody to-NADH dehydrogenase (ubiquinone) Fe-S protein 3 |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
30kDa (NADH-coenzyme Q reductase), CI-30, NADH to ubiquinone and biological process this GO :0008137 and NADH dehydrogenase (ubiquinone) activity and molecular function this GO :0009055 and electron carrier activity and molecular function this GO :0016651 and oxidoreductase activity, NDUFS3 and IDBG-239864 and ENSG00000213619 and 4722, NDUFS3 and IDBG-637482 and ENSBTAG00000018483 and 287327, Ndufs3 and IDBG-189838 and ENSMUSG00000005510 and 68349, acting on NAD(P)H, acting on NAD(P)H, acting on NAD(P)H and molecular function this GO :0021762 and substantia nigra development and biological process this GO :0022904 and respiratory electron transport chain and biological process this GO :0030308 and negative regulation of cell growth and biological process this GO :0031966 and mitochondrial membrane and cellular component this GO :0044237 and cellular metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0072593 and reactive oxygen species metabolic process and biological process this GO :2001243 and negative regulation of intrinsic apoptotic signaling pathway and biological process, nuclei, oxidoreductase activity, this GO :0003954 and NADH dehydrogenase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005743 and mitochondrial inner membrane and cellular component this GO :0005747 and mitochondrial respiratory chain complex I and cellular component this GO :0006120 and mitochondrial electron transport, this GO :0003954 : NADH dehydrogenase activity, this GO :0003954 : NADH dehydrogenase activity and also this GO :0005515 : protein binding and also this GO :0008137 : NADH dehydrogenase (ubiquinone) activity and also this GO :0009055 : electron carrier activity and also this GO :0016651 : oxidoreductase activity, this GO :0005515 : protein binding, this GO :0008137 : NADH dehydrogenase (ubiquinone) activity, this GO :0009055 : electron carrier activity, this GO :0016651 : oxidoreductase activity, NADH dehydrogenase (ubiquinone) Fe-S protein 3 |
| Identity: |
7710 |
| Gene: |
NDUFS3 |
More about : NDUFS3 |
| Long gene name: |
NADH:ubiquinone oxidoreductase core subunit S3 |
| Synonyms gene name: |
30kDa (NADH-coenzyme Q reductase) , NADH dehydrogenase (ubiquinone) Fe-S protein 3 (30kD) (NADH-coenzyme Q reductase) NADH dehydrogenase (ubiquinone) Fe-S protein 3 |
| Synonyms name: |
complex I 30kDa subunit NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial |
| Locus: |
11p11, 2 |
| Discovery year: |
1995-11-08 |
| GenBank acession: |
AF067139 |
| Entrez gene record: |
4722 |
| Pubmed identfication: |
9763677 |
| RefSeq identity: |
NM_004551 |
| Classification: |
NADH:ubiquinone oxidoreductase core subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000166893 |