| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
GPX1 |
| Specificity: |
This antibody reacts specifically with GPX1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse Glutathione Peroxidase 1 |
| Gene ID: |
14775 |
| Swiss Prot: |
P11352 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
It contains a selenocysteine (Sec) residue at its active site, The 3' UTR of Sec-containing genes have a common stem-loop structure, The selenocysteine is encoded by the UGA codon, [provided by RefSeq], the sec insertion sequence (SECIS), which functions in the detoxification of hydrogen peroxide, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal, which normally signals translation termination, This gene product belongs to the family of glutathione peroxidase |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Also known as: |
GPX1 Polyclonal Antibody |
| Other name: |
Anti-GPX1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
GPX1 |
| Short name: |
Anti-GPX1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-glutathione peroxidase 1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
GPX1 and IDBG-305033 and ENSG00000233276 and 2876, GPXD and GSHPX1, Gpx1 and IDBG-199664 and ENSMUSG00000063856 and 14775, epigenetic and biological process this GO :0042311 and vasodilation and biological process this GO :0042542 and response to hydrogen peroxide and biological process this GO :0042744 and hydrogen peroxide catabolic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043154 and negative regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043295 and glutathione binding and molecular function this GO :0043403 and skeletal muscle tissue regeneration and biological process this GO :0043523 and regulation of neuron apoptotic process and biological process this GO :0043534 and blood vessel endothelial cell migration and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045454 and cell redox homeostasis and biological process this GO :0047066 and phospholipid-hydroperoxide glutathione peroxidase activity and molecular function this GO :0048741 and skeletal muscle fiber development and biological process this GO :0051450 and myoblast proliferation and biological process this GO :0051593 and response to folic acid and biological process this GO :0051702 and interaction with symbiont and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0055086 and nucleobase-containing small molecule metabolic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0060047 and heart contraction and biological process this GO :0060055 and angiogenesis involved in wound healing and biological process this GO :0061136 and regulation of proteasomal protein catabolic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0090201 and negative regulation of release of cytochrome c from mitochondria and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :1902176 and negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway and biological process, nuclei, phospholipid-hydroperoxide glutathione peroxidase activity, this GO :0000302 and response to reactive oxygen species and biological process this GO :0001659 and temperature homeostasis and biological process this GO :0001885 and endothelial cell development and biological process this GO :0002862 and negative regulation of inflammatory response to antigenic stimulus and biological process this GO :0004602 and glutathione peroxidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0005829 and cytosol and cellular component this GO :0006144 and purine nucleobase metabolic process and biological process this GO :0006195 and purine nucleotide catabolic process and biological process this GO :0006629 and lipid metabolic process and biological process this GO :0006641 and triglyceride metabolic process and biological process this GO :0006749 and glutathione metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0006982 and response to lipid hydroperoxide and biological process this GO :0007568 and aging and biological process this GO :0007605 and sensory perception of sound and biological process this GO :0008283 and cell proliferation and biological process this GO :0008430 and selenium binding and molecular function this GO :0008631 and intrinsic apoptotic signaling pathway in response to oxidative stress and biological process this GO :0009410 and response to xenobiotic stimulus and biological process this GO :0009609 and response to symbiotic bacterium and biological process this GO :0009611 and response to wounding and biological process this GO :0009636 and response to toxic substance and biological process this GO :0009650 and UV protection and biological process this GO :0009725 and response to hormone and biological process this GO :0009749 and response to glucose and biological process this GO :0010269 and response to selenium ion and biological process this GO :0010332 and response to gamma radiation and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014902 and myotube differentiation and biological process this GO :0017124 and SH3 domain binding and molecular function this GO :0018158 and protein oxidation and biological process this GO :0019369 and arachidonic acid metabolic process and biological process this GO :0019372 and lipoxygenase pathway and biological process this GO :0032355 and response to estradiol and biological process this GO :0033194 and response to hydroperoxide and biological process this GO :0033599 and regulation of mammary gland epithelial cell proliferation and biological process this GO :0035094 and response to nicotine and biological process this GO :0040029 and regulation of gene expression, this GO :0004602 : glutathione peroxidase activity, this GO :0004602 : glutathione peroxidase activity and also this GO :0005515 : protein binding and also this GO :0008430 : selenium binding and also this GO :0017124 : SH3 domain binding and also this GO :0043295 : glutathione binding and also this GO :0047066 : phospholipid-hydroperoxide glutathione peroxidase activity, this GO :0005515 : protein binding, this GO :0008430 : selenium binding, this GO :0017124 : SH3 domain binding, this GO :0043295 : glutathione binding, this GO :0047066 : phospholipid-hydroperoxide glutathione peroxidase activity, glutathione peroxidase 1 |
| Identity: |
4553 |
| Gene: |
GPX1 |
More about : GPX1 |
| Long gene name: |
glutathione peroxidase 1 |
| Locus: |
3p21, 31 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
2876 |
| Pubmed identfication: |
9605859 |
| RefSeq identity: |
NM_000581 |
| Classification: |
Selenoproteins |
| Havana BLAST/BLAT: |
OTTHUMG00000156837 |