| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
PLAA/Phospholipase A2 activator protein |
| Specificity: |
This antibody reacts specifically with PLAA |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Phospholipase A2 activator protein |
| Gene ID: |
9373 |
| Swiss Prot: |
Q9Y263 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Also known as a pro-inflammatory agent, As such, PLAP has been found in inflamed tissues and synovial fluid from patients with rheumatoid arthritis, The formation of PLAP can be stimulated by IL-1 beta and TNF-alpha, activates PLA2 (phospholipase A2 enzyme) and is an important mediator of eicosanoid generation, it is believed to play an important role in the regulation of inflammatory diseases, Phospholipase A2 activator protein (PLAP) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PLAP PLA2P FLJ11281 FLJ12699 DOA1 |
| Also known as: |
PLAA Polyclonal Antibody |
| Other name: |
Anti-PLAA Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
PLAA |
| Short name: |
Anti-PLAA (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-PLAA (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9043 |
| Gene: |
PLAA |
More about : PLAA |
| Long gene name: |
phospholipase A2 activating protein |
| Synonyms name: |
DOA1 homolog (S, cerevisiae) |
| Locus: |
9p21, 2 |
| Discovery year: |
1999-04-15 |
| GenBank acession: |
AF083395 |
| Entrez gene record: |
9373 |
| Pubmed identfication: |
9931468 10644453 |
| RefSeq identity: |
NM_001031689 |
| Classification: |
WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000019708 |