| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RAE1 |
| Specificity: |
This antibody reacts specifically with RAE1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RAE1 |
| Gene ID: |
8480 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternatively spliced transcript variants encoding the same protein have been found for this gene, Depletion of Rae1 from extracts or cells severely inhibits mitotic spindle assembly, It contains four WD40 motifs, This gene is thought to be involved in nucleocytoplasmic transport, and has been shown to localize to distinct foci in the nucleoplasm, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton, and to meshwork-like structures throughout the cytoplasm, suggesting that the encoded proteins are involved in RNA export, to the nuclear rim, Mutations in Rae1 and Gle2(Saccharomyces cerevisae homolog) genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Mnrp41 |
| Also known as: |
RAE1 Polyclonal Antibody |
| Other name: |
Anti-RAE1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RAE1 |
| Short name: |
Anti-RAE1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RAE1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9828 |
| Gene: |
RAE1 |
More about : RAE1 |
| Long gene name: |
ribonucleic acid export 1 |
| Synonyms gene name: |
RAE1 (RNA export 1, S, pombe) , pombe) homolog RAE1 RNA export 1 homolog (S |
| Locus: |
20q13, 31 |
| Discovery year: |
1999-07-23 |
| GenBank acession: |
U84720 |
| Entrez gene record: |
8480 |
| Pubmed identfication: |
9370289 9256445 |
| Classification: |
Nucleoporins WD repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000032819 |