| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DRAK2 |
| Specificity: |
This antibody reacts specifically with DRAK2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DRAK2 |
| Gene ID: |
9262 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Certain serine/threonine protein kinases, DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues, DRAKs contain an N terminal kinase domain and a C terminal regulation domain, DRAKs have high sequence homology to DAP and ZIP kinases, Overexpression of DRAK2 induces apoptosis, Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases), and they represent a novel family of serine/threonine kinases, are mediators of apoptosis, such as ASK1 and RIP, which mediates apoptosis through their catalytic activities, Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
DRAK2 |
| Also known as: |
DRAK2 Polyclonal Antibody |
| Other name: |
Anti-DRAK2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DRAK2 |
| Short name: |
Anti-DRAK2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-DRAK2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11396 |
| Gene: |
STK17B |
More about : STK17B |
| Long gene name: |
serine/threonine kinase 17b |
| Synonyms gene name: |
serine/threonine kinase 17b (apoptosis-inducing) |
| Synonyms name: |
death-associated protein kinase-related 2 |
| Locus: |
2q32, 3 |
| Discovery year: |
1999-05-21 |
| GenBank acession: |
AB011421 |
| Entrez gene record: |
9262 |
| Pubmed identfication: |
9786912 |
| Classification: |
Death associated protein kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000132735 |