| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
p63 Ser455 |
| Specificity: |
This antibody reacts specifically with p63 (Ser455) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser455 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human p63 around the phosphorylation site of Ser455 |
| Gene ID: |
8626 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
ADULT syndrome (acro-dermato-ungual-lacrimal-tooth), An animal model, Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins, Jul 2008], Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined, Mutations in this gene are associated with ectodermal dysplasia, Rap-Hodgkin syndrome (RHS), [provided by RefSeq, and cleft lip/palate syndrome 3 (EEC3), and orofacial cleft 8, ankyloblepharon-ectodermal defects-cleft lip/palate, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues, limb-mammary syndrome, p63 -/- mice, p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, split-hand/foot malformation 4 (SHFM4), such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium, This gene encodes a member of the p53 family of transcription factors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
AIS, Amplied in squamous cell carcinoma, Bp51A, Bp51B, CUSP, Chronic ulcerative stomatitis protein, DN p63 alpha 1, DNp63, EEC3, KET, Keratinocyte transcription factor, Keratinocyte transcription factor KET, LMS, NBP, OFC8, P51/P63, P63_HUMAN, P73, RHS, SHFM4, TP53CP, TP53L, TP63, TP73, TP73L, Transformation related protein 63, Trp53rp1, Trp63, Tumor protein 63, Tumor protein p53-competing protein, Tumor protein p53-like, Tumor protein p73, p-p63 Ser455, p40, p51, p53 like transcription factor, p53 related protein, p53-related protein p63, p53CP, p63, p63 Alpha, p63 phospho Ser455, p73H, p73L, tumor protein 63 kDa with strong homology to p53, tumor protein p63, tumor protein p73-like, p63 phospho S455 |
| Also known as: |
p63 (Ser455) Polyclonal Antibody |
| Other name: |
Anti-p63 (Ser455) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
p63 (Ser455) |
| Short name: |
Anti-p63 (Ser455) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-p63 (Ser455) (polyclonal) |
| Alternative technique: |
polyclonals |