| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
P53 Ser9 |
| Specificity: |
This antibody reacts specifically with P53 (Ser9) |
| Modification: |
Phosphorylation |
| Modification site: |
Ser9 |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic phosphopeptide derived from human P53 around the phosphorylation site of Ser9 |
| Gene ID: |
7157 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
20937277), Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms, DNA binding, DNA repair, Feb 2013], Mutations in this gene are associated with a variety of human cancers, The encoded protein responds to diverse cellular stresses to regulate expression of target genes, [provided by RefSeq, and oligomerization domains, apoptosis, including hereditary cancers such as Li-Fraumeni syndrome, or changes in metabolism, senescence, thereby inducing cell cycle arrest, This gene encodes a tumor suppressor protein containing transcriptional activation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
p53 LFS1 |
| Also known as: |
P53 (Ser9) Polyclonal Antibody |
| Other name: |
Anti-P53 (Ser9) Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
P53 (Ser9) |
| Short name: |
Anti-P53 (Ser9) (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-P53 (Ser9) (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
11998 |
| Gene: |
TP53 |
More about : TP53 |
| Long gene name: |
tumor protein p53 |
| Synonyms name: |
Li-Fraumeni syndrome |
| Locus: |
17p13, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
AF307851 |
| Entrez gene record: |
7157 |
| Pubmed identfication: |
6396087 3456488 2047879 |
| RefSeq identity: |
NM_000546 |
| Havana BLAST/BLAT: |
OTTHUMG00000162125 |
| Locus Specific Databases: |
IARC TP53 Mutation Database p53 UMD TP53 mutation database Database of Germline p53 Mutations MUTP53LOAD, Mutant p53 Loss Of Activity Database LRG_321 |