| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
CETP |
| Specificity: |
This antibody reacts specifically with CETP |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human CETP |
| Gene ID: |
1071 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
CETP has an important role in reverse cholesterol transport and shaping and affecting the composition of plasma lipoproteins, CETP is responsible for neutral lipid transfer activity in plasma in numerous species, In general elevated levels of CETP have been associated with increased risk of coronary heart disease, Since CETP is able to accelerate specifically the exchange of lipid components between pro- and anti-atherogenic lipoprotein fractions, This mechanism, is physiologically important because it maintains systemic cholesterol levels, it may be a key determinant of the global atherogenicity of the plasma lipoprotein profile and arises as a possible target in atherosclerosis prevention, referred to as reverse cholesterol transport, High density lipoproteins (HDLs) have been proposed to function jointly with lecithin:cholesterol acyltransferase and CETP to facilitate cholesterol transport from tissues to the liver |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
BPIFF |
| Also known as: |
CETP Polyclonal Antibody |
| Other name: |
Anti-CETP Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
CETP |
| Short name: |
Anti-CETP (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, plasma (polyclonal), antibody to-cholesteryl ester transfer protein |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BPIFF and HDLCQ10, CETP and IDBG-32674 and ENSG00000087237 and 1071, Extracellular, phosphatidylcholine binding, plasma, this GO :0005319 and lipid transporter activity and molecular function this GO :0005548 and phospholipid transporter activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0006641 and triglyceride metabolic process and biological process this GO :0006869 and lipid transport and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008289 and lipid binding and molecular function this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010874 and regulation of cholesterol efflux and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0015914 and phospholipid transport and biological process this GO :0017127 and cholesterol transporter activity and molecular function this GO :0017129 and triglyceride binding and molecular function this GO :0030301 and cholesterol transport and biological process this GO :0031210 and phosphatidylcholine binding and molecular function this GO :0031982 and vesicle and cellular component this GO :0034364 and high-density lipoprotein particle and cellular component this GO :0034372 and very-low-density lipoprotein particle remodeling and biological process this GO :0034374 and low-density lipoprotein particle remodeling and biological process this GO :0034375 and high-density lipoprotein particle remodeling and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0043691 and reverse cholesterol transport and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0046470 and phosphatidylcholine metabolic process and biological process this GO :0055088 and lipid homeostasis and biological process this GO :0055091 and phospholipid homeostasis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070328 and triglyceride homeostasis and biological process, this GO :0005319 : lipid transporter activity, this GO :0005319 : lipid transporter activity and also this GO :0005548 : phospholipid transporter activity and also this GO :0008289 : lipid binding and also this GO :0015485 : cholesterol binding and also this GO :0017127 : cholesterol transporter activity and also this GO :0017129 : triglyceride binding and also this GO :0031210 : phosphatidylcholine binding, this GO :0005548 : phospholipid transporter activity, this GO :0008289 : lipid binding, this GO :0015485 : cholesterol binding, this GO :0017127 : cholesterol transporter activity, this GO :0017129 : triglyceride binding, this GO :0031210 : phosphatidylcholine binding, cholesteryl ester transfer protein |
| Identity: |
1869 |
| Gene: |
CETP |
More about : CETP |
| Long gene name: |
cholesteryl ester transfer protein |
| Synonyms gene name: |
cholesteryl ester transfer protein, plasma |
| Synonyms name: |
BPI fold containing family F |
| Locus: |
16q13 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M30185 |
| Entrez gene record: |
1071 |
| Pubmed identfication: |
3600759 2334701 |
| RefSeq identity: |
NM_000078 |
| Classification: |
BPI fold containing |
| Havana BLAST/BLAT: |
OTTHUMG00000133279 |