| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
BMP6 |
| Specificity: |
This antibody reacts specifically with BMP6 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human BMP6 |
| Gene ID: |
654 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site, Based on its expression early in embryogenesis, In addition, Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily, [provided by RefSeq], the BMP encoded by this gene has a proposed role in early development, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity, The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
VGR1 |
| Also known as: |
BMP6 Polyclonal Antibody |
| Other name: |
Anti-BMP6 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
BMP6 |
| Short name: |
Anti-BMP6 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-bone morphogenetic protein 6 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
BMP receptor binding, BMP6 and IDBG-60018 and ENSG00000153162 and 654, BMP6 and IDBG-636350 and ENSBTAG00000019234 and 617566, Bmp6 and IDBG-145907 and ENSMUSG00000039004 and 12161, Extracellular, VGR and VGR1, this GO :0001501 and skeletal system development and biological process this GO :0001503 and ossification and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001654 and eye development and biological process this GO :0001822 and kidney development and biological process this GO :0001938 and positive regulation of endothelial cell proliferation and biological process this GO :0001958 and endochondral ossification and biological process this GO :0003323 and type B pancreatic cell development and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0008083 and growth factor activity and molecular function this GO :0010039 and response to iron ion and biological process this GO :0010862 and positive regulation of pathway-restricted SMAD protein phosphorylation and biological process this GO :0014823 and response to activity and biological process this GO :0030154 and cell differentiation and biological process this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030539 and male genitalia development and biological process this GO :0031988 and membrane-bounded vesicle and cellular component this GO :0032026 and response to magnesium ion and biological process this GO :0032332 and positive regulation of chondrocyte differentiation and biological process this GO :0032349 and positive regulation of aldosterone biosynthetic process and biological process this GO :0032526 and response to retinoic acid and biological process this GO :0040007 and growth and biological process this GO :0045603 and positive regulation of endothelial cell differentiation and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0050679 and positive regulation of epithelial cell proliferation and biological process this GO :0050714 and positive regulation of protein secretion and biological process this GO :0051216 and cartilage development and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0060395 and SMAD protein signal transduction and biological process this GO :0070700 and BMP receptor binding and molecular function this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :2000105 and positive regulation of DNA-dependent DNA replication and biological process this GO :2000860 and positive regulation of aldosterone secretion and biological process, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0005515 : protein binding and also this GO :0008083 : growth factor activity and also this GO :0046982 : protein heterodimerization activity and also this GO :0070700 : BMP receptor binding, this GO :0005515 : protein binding, this GO :0008083 : growth factor activity, this GO :0046982 : protein heterodimerization activity, this GO :0070700 : BMP receptor binding, bone morphogenetic protein 6 |
| Identity: |
1073 |
| Gene: |
BMP6 |
More about : BMP6 |
| Long gene name: |
bone morphogenetic protein 6 |
| Synonyms gene: |
VGR |
| Synonyms gene name: |
vegetal related growth factor (TGFB-related) |
| Locus: |
6p24, 3 |
| Discovery year: |
1991-06-05 |
| GenBank acession: |
AF083030 |
| Entrez gene record: |
654 |
| Pubmed identfication: |
1427904 1453478 |
| RefSeq identity: |
NM_001718 |
| Classification: |
Endogenous ligands Bone morphogenetic proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000014217 |