| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
JAM1 |
| Specificity: |
This antibody reacts specifically with JAM1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Junctional Adhesion Molecule 1 |
| Gene ID: |
50848 |
| Swiss Prot: |
Q9Y624 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Appears early in primordial forms of cell junctions and recruits PARD3, In case of orthoreovirus infection, Involved in platelet activation, Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier, The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, serves as receptor for the virus, thereby preventing tight junction assembly (By similarity), Seems to play a role in epithelial tight junction formation |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
PAM-1 JCAM JAM-1 JAM-A JAMA CD321 |
| Also known as: |
JAM1 Polyclonal Antibody |
| Other name: |
Anti-JAM1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
JAM1 |
| Short name: |
Anti-JAM1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-JAM1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
14685 |
| Gene: |
F11R |
More about : F11R |
| Long gene name: |
F11 receptor |
| Synonyms gene: |
JAM1 |
| Synonyms gene name: |
junctional adhesion molecule 1 |
| Locus: |
1q23, 3 |
| Discovery year: |
2001-04-10 |
| GenBank acession: |
AF111713 |
| Entrez gene record: |
50848 |
| Pubmed identfication: |
10395639 7646439 |
| RefSeq identity: |
NM_016946 |
| Classification: |
Immunoglobulin like domain containing CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000028602 |